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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRJ All Species: 8.48
Human Site: Y1220 Identified Species: 18.67
UniProt: Q12913 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12913 NP_002834.3 1337 145941 Y1220 D L L I N F R Y L V R D Y M K
Chimpanzee Pan troglodytes XP_508422 1337 145901 Y1220 D L L I N F R Y L V R D Y M K
Rhesus Macaque Macaca mulatta XP_001117453 2215 249296 F1822 K P L Y S D T F F S L P I T T
Dog Lupus familis XP_540737 1221 135739 L1105 L L I N F R Y L V R D Y M K Q
Cat Felis silvestris
Mouse Mus musculus Q64455 1238 136750 L1122 L L I N F R Y L V R D Y M K Q
Rat Rattus norvegicus Q64612 1711 187274 E1331 S S L L A F V E L V Q E Q V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513469 1278 143135 Y1161 D L L I N F R Y L V H D F K K
Chicken Gallus gallus Q9W6V5 1406 154195 H1289 D L L I N F R H L V H E Y S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IFW2 1909 213435 R1533 T P I L A F L R R V K A C N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35992 1631 185062 R1451 Q T L V R F V R A F R D R I G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9BMN8 2200 246601 K1826 T P F L I F L K R V K T L N P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 23.7 67 N.A. 67.6 20.3 N.A. 56.1 44.1 N.A. 20.1 N.A. 23.8 N.A. 20.2 N.A.
Protein Similarity: 100 99.6 38.1 75.4 N.A. 75.6 35.3 N.A. 67.3 58.2 N.A. 33.5 N.A. 40 N.A. 33 N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 6.6 26.6 N.A. 80 66.6 N.A. 13.3 N.A. 26.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 20 26.6 N.A. 26.6 60 N.A. 86.6 80 N.A. 33.3 N.A. 40 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 37 0 0 0 0 10 0 0 0 0 19 37 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 19 0 0 0 % E
% Phe: 0 0 10 0 19 73 0 10 10 10 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 19 0 0 0 0 % H
% Ile: 0 0 28 37 10 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 10 0 0 0 0 0 0 10 0 0 19 0 0 28 28 % K
% Leu: 19 55 64 28 0 0 19 19 46 0 10 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 19 19 0 % M
% Asn: 0 0 0 19 37 0 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 28 0 0 0 0 0 0 0 0 0 10 0 0 19 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 10 0 10 0 28 % Q
% Arg: 0 0 0 0 10 19 37 19 19 19 28 0 10 0 0 % R
% Ser: 10 10 0 0 10 0 0 0 0 10 0 0 0 10 10 % S
% Thr: 19 10 0 0 0 0 10 0 0 0 0 10 0 10 10 % T
% Val: 0 0 0 10 0 0 19 0 19 64 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 19 28 0 0 0 19 28 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _